Research Integrity Should Not Mean Its Weaponization

As somebody working to promote research integrity who has lived in several authoritarian countries, the growing weaponization of research integrity against political opponents feels unpleasantly familiar. Increasingly, those seeking to intimidate or harass academics are singling them out for research integrity audits. There is a parallel to the way in which authoritarian governments use the tax police to intimidate or harass their critics.

Why the tax police? Let me explain. When an authoritarian government wants to cut ambitious businesspeople down to size, or bring independent media outlets or meddlesome human rights NGOs to heel, the first step is often to send in the tax police. Meticulously sifting through gigabytes of data covering multiple years of operations, inspectors are bound to find some minor violation of the complex tax code. Voila! The critics’ organizations are shut down, their assets seized, and guilty individuals thrown into jail. Even if meticulous tax audits find no clear-cut violation, the government can continue harassing opponents by filing a barrage of spurious legal cases that sully their reputation and remind everyone else to mind the red lines.

In short, you first choose the target, and then you go looking for the crime.

This is exactly what happened to professor Claudine Gay, who recently resigned as Harvard’s president. She landed in the crosshairs of critics when, during Congressional testimony, she was widely seen to insufficiently condemn antisemitism on campus. With dreary predictability, the issue became embroiled in America’s culture wars. Those on the political right derided her as a ‘woke hire’ and called for her head, while voices on the left denounced “political theatrics advancing a White supremacist agenda.“

Subsequently, a conservative blog raised allegations of research misconduct. Its opening lines pulled no punches:

It went on to discuss the research integrity violation:

Set on the case, the auditors swooped in. The right-wing Washington Free Beacon reported that it worked with nearly a dozen scholars to sift through her work and analyze potential cases of plagiarism. The Republican chair of a congressional committee then requested internal emails from the university “concerning allegations of plagiarism.”

The infractions were real but minor. An internal investigation by Harvard concluded that these cases of “inadequate citation” did not amount to research misconduct, but nonetheless requested corrections to Gay’s work. A heated (legitimate) debate ensued about whether Harvard faculty were being held to lower standards than their students.

Accusing prominent academics of political heresy has a long history stretching back at least to the communist witch hunts of the McCarthy era. The charges leveled at Gay from the political right of “overseeing a racist admissions program” and “failing to stand up to rampant anti-Semitism” fall squarely into this tradition, as do left-wing attempts to smear academics who criticized the shortcomings of her scholarship as white supremacists.

What is new, however, is the weaponization of research integrity in these battles. In the 1950s, it never occurred to McCarthy to audit his targets’ ethics approval documentation. Today, this has become routine.

Thus, when French scientist Didier Raoult during spring 2020 claimed that hydroxychloroquine was effective for treating COVID patients, as is common in the wake of major new scientific claims, many academics carefully scrutinized the methodology of his study. However, hydroxychloroquine was also a political red flag because President Trump was loudly promoting the unproven treatment at the same time. This put research integrity auditors onto Raoult’s case. They scrutinized his entire portfolio of publications and found numerous serious violations of research integrity standards at the institute he ran, including failures to secure ethics approval for hundreds of studies.

What is the problem? I see three areas of concern:

First and foremost, as authoritarian governments have long known, responding to criticism by digging for dirt has a chilling effect on academic freedom and freedom of speech. My guess is that very few senior academics can be 100 percent confident that every single research project and publication that they were ever involved in over the course of decades consistently and fully met the exacting research integrity standards that were applied to Gay’s work. When virtually everyone might be guilty, nobody is safe. If saying or publishing anything that could offend anybody can trigger a forensic audit and possible public and professional disgrace, the only safe course of action is to avoid fields of study, topics and conclusions that are ‘dangerous’.

Second, fear of the research integrity police will lead to publication bias. Currently, this chiefly applies to culture war issues like race, sex and gender, where publishing ‘problematic’ findings routinely draws hostile fire from the political left. However, more than one player can play the persecution game. Powerful companies too, have a long history of actively trying to shape the narrative and science around their products.

In the future, academics who find evidence that a highly profitable drug has dangerous side effects might think twice about publishing their research, lest the pharma company involved goes through their entire past publication record with a research integrity toothcomb. Similarly, if there are dozens of conflicting studies of a product’s safety, a company could selectively audit those whose conclusions it dislikes, and then try to get those retracted from the scientific record. (Such selective purges are already underway for studies whose conclusions are deemed to be racist or sexist)

Third, focusing research integrity efforts on targets selected by partisan actors or social media mobs is unlikely to improve science. True, research integrity sleuths have succeeded in uncovering serious violations committed under Raoult’s watch. However, this focus on one offender’s sins distracts from the far more alarming fact that hundreds of blatant violations went completely undetected over many years.

A more productive approach would be to systematically assess how widespread violations are across an entire field, determine which types of violations cause the greatest harm, sanction the worst offenders, and then build systems to prevent it from happening again. In other words, rather than conducting isolated hit-and-run jobs, we should be pursuing what auditors call a risk-based approach.

Taking research integrity seriously means focusing on and addressing the most serious research integrity violations. And that rarely happens.

Take my own field of research, clinical trial transparency. Currently, American researchers neglect to publish the results of over a third of all clinical trials that they run. Over the past 20 years, probably over 100,000 studies worldwide have remained unpublished. It is well documented that the resulting gaps and distortions in the medical evidence base significantly harm patients. Non-publication of clinical trial results is also a clear violation of medical research ethics.

Furthermore, these violations are easy to identify. Numerous studies and datasets list hundreds of trials that have remained unpublished. Nonetheless, to the best of my knowledge, only one ethics complaint has ever been filed over an unreported trial result, and the UK is so far the only country in the world to systematically tackle the problem.

Meanwhile, following right-wing celebrations of Gay’s downfall, the important questions her case raised about where exactly institutions draw research integrity red lines and how they respond to complaints will quickly fade into the background. Gay herself is returning to her old job as a Harvard professor. A few references have been added to her publications, but no, science has not improved.

If we want to improve research integrity, first choosing a specific person to target and then looking for the crime is the wrong approach.